A recent study reveals that individuals who discontinue popular slimming jabs like Mounjaro or Wegovy can put back on reduced body mass much more quickly than those who halt conventional diet and exercise plans.
Published data in a prominent health publication demonstrates that while overweight individuals frequently drop about a fifth of their total mass while using the jabs, the weight returns at an average rate of 0.8 kg per month upon discontinuation.
"Individuals purchasing these medications should be cognizant of the risk of fast rebound weight gain when the therapy concludes," warns expert Dr. Susan Jebb.
That rate of regain implies a reversion to pre-treatment mass within about 18 months.
Comparing Therapies
The study, which looked at dozens of studies involving over 9,000 of participants, contrasted the results of GLP-1 agonists with older methods.
The team emphasize that people who shed pounds through diet and exercise typically experience a more gradual creep back—approximately 0.1 kg a month—once they finish.
Understanding the Fast Rebound
Experts propose the way of the drugs accounts for the amplified weight return.
The injections copy a natural hormone called glucagon-like peptide-1, which controls appetite.
"Sustained high doses of GLP-1 levels several times higher than the body's typical production might result in the body to produce less of its own natural GLP-1, and may also diminish sensitivity to its actions," noted Dr. Adam Collins, a nutrition specialist.
"Withdrawal of this hormone supplement means appetite is no longer kept in check, making binge eating far more likely."
A Lifelong Disease?
Health authorities suggest the injections for people with weight-linked health risks, accompanied by recommended diet and exercise modifications.
Professionals contend that, given the high risk of relapse, the treatment is often ongoing.
This perspective is echoed by drug manufacturers, who note that the results "underscore the chronic nature of excess weight," similar to managing conditions like hypertension.
User Testimonies
Individuals who have stopped the medication report a intense return of appetite.
"It was like something that goes on and I was suddenly ravenous," said one woman.
This challenge is worsened if patients have not developed lasting lifestyle or habit changes during therapy.
Widespread Adoption
Recent estimates show that a significant number of people in the UK have used these injections in the last 12 months, with desire being substantial.
- Adoption is higher among females compared to men.
- The 40s and 50s age group shows the highest usage rates.
- Many obtain the drugs through private prescriptions rather than the NHS.
In conclusion, researchers emphasize that while the jabs are effective tools for weight loss, they are not a standalone cure and maintained weight loss likely depends on integrated behavioural support.
